Homeowners can attempt to get rid of horse flies, but in most cases, it's a good idea to hire some professionals. To try to get rid of horse flies, homeowners can purchase traps and place them in areas where horse flies are known to hang out and breed. By catching the horse flies in traps, they cannot attack humans or animals. When working in any area that is likely to contain horse flies, it's important to wear long pants and sleeves. Although protective clothing will not stop the bite from a horsefly, it will lessen the severity of a bite.